Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25573050 | 0.78 | GAA (0.41) | CA1CA2CA9 | |
| SCHEMBL29866474 | 0.78 | GAA (0.41) | CA1CA2CA9 | |
| SCHEMBL14498187 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1494414 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28339333 | 0.74 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL3384694 | 0.72 | ACHE (0.43) | ALDH1A1 | |
| SCHEMBL1494426 | 0.71 | ALDH1A1 (0.38) | CA1ALDH1A1 | |
| SCHEMBL30699773 | 0.71 | ALDH1A1 (0.38) | CA1ALDH1A1 | |
| SCHEMBL8840849 | 0.70 | RAPGEF4 (0.39) | CA1CA2ALDH1A1 | |
| SCHEMBL22102332 | 0.70 | RAPGEF4 (0.39) | CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012396-A1 | 5,6 SUBSTITUTED BENZAMIDE DERIVATIVES AS MODULATORS OF THE EP<SB>2 </SB>RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | disclosed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |