SCHEMBL29866545

SCHEMBL29866545

Fc1cc(CCl)cc(N2CCOCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR183 P32249 1/20 0.43
AGXT P21549 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ACLY P53396 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
PIK3CA P42336 4/20 0.38
AKT1 P31749 3/20 0.38
MTOR P42345 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23662602 1.00 GPR183 (0.43) GPR183AGXTKDM4EACLYLMNA
SCHEMBL1662765 0.87 GPR183 (0.45) GPR183AGXTKDM4EACLYLMNA
SCHEMBL672007 0.83 GPR183 (0.43) GPR183AGXTKDM4EACLYLMNA
SCHEMBL12831239 0.83 KDM4E (0.44) GPR183AGXTKDM4EACLYLMNA
SCHEMBL3508314 0.82 KDM4E (0.50) GPR183KDM4EACLYLMNAHSD17B10
SCHEMBL6688959 0.81 GPR183 (0.46) GPR183AGXTKDM4ELMNAMEN1
SCHEMBL6629681 0.81 GPR183 (0.44) GPR183AGXTKDM4EACLYLMNA
SCHEMBL27885766 0.81 GPR183 (0.44) GPR183AGXTKDM4EACLYLMNA
SCHEMBL23662642 0.80 GPR183 (0.43) GPR183AGXTKDM4EACLYLMNA
SCHEMBL17548029 0.77 ACLY (0.54) GPR183KDM4EACLYLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
CN-115066428-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-09-16 CN disclosed