Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | CTSA | P10619 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151907 | 0.76 | SUCNR1 (0.48) | SLC1A3SLC1A2SLC1A1HDAC1HDAC2 | |
| SCHEMBL14081313 | 0.71 | CTSA (0.45) | CTSA | |
| SCHEMBL21783868 | 0.70 | FFAR1 (0.39) | FFAR1PTGS2 | |
| SCHEMBL18201611 | 0.66 | L3MBTL1 (0.41) | CTSAFFAR1 | |
| SCHEMBL5151913 | 0.66 | SUCNR1 (0.60) | NR1H4PTGS2 | |
| SCHEMBL20545291 | 0.66 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1CTSAMME | |
| SCHEMBL20545289 | 0.66 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1CTSAMME | |
| SCHEMBL2470223 | 0.66 | HDAC1 (0.53) | SLC1A3SLC1A2SLC1A1HDAC1HDAC2 | |
| SCHEMBL20545547 | 0.65 | CTSA (0.59) | SLC1A3SLC1A2SLC1A1CTSAMCL1 | |
| SCHEMBL20545545 | 0.65 | CTSA (0.59) | SLC1A3SLC1A2SLC1A1CTSAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447449-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-09-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447449-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | IDO1, IDO2, INMT | SLC1A3 1258/4885SLC1A2 541/4885SLC1A1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.