Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160265 | 0.88 | THRB (0.40) | SLC1A3SLC1A2SLC1A1FFAR3MMP1 | |
| SCHEMBL1196063 | 0.88 | THRB (0.40) | SLC1A3SLC1A2SLC1A1FFAR3MMP1 | |
| SCHEMBL387178 | 0.88 | THRB (0.40) | SLC1A3SLC1A2SLC1A1FFAR3MMP1 | |
| Glycolic Acid SCHEMBL28099037 | 0.84 | FFAR3 (0.35) | SLC1A3SLC1A2SLC1A1FFAR3MMP1 | |
| SCHEMBL27800200 | 0.77 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1GABRPGABRD | |
| Sarcosine SCHEMBL29869275 | 0.77 | EGLN1 (0.37) | — | |
| SCHEMBL9628984 | 0.76 | MMP1 (0.48) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| SCHEMBL26940409 | 0.76 | MMP1 (0.48) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| Glycine SCHEMBL868216 | 0.76 | LMNA (0.52) | GLRA1SLC6A9OR51E2GABRPGABRD | |
| SCHEMBL7069046 | 0.74 | LMNA (0.38) | SLC1A3SLC1A2SLC1A1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4595776-A1 | NUTRITIONAL COMPOSITION FOR CANCER PATIENTS AND ELDERLY SUBJECTS | Pasqualetti, Giuseppe (IT) | 2025-08-06 | — | — | EP | disclosed |
| CN-110133130-B | Method for detecting and analyzing artificially synthesized estrogen substance in human urine | 上海大学 | 2022-12-23 | — | — | CN | disclosed |
| EP-3424502-B1 | AQUAPORIN 4 FUNCTION PROMOTER AND PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS | UNIV NIIGATA (JP) | 2022-10-19 | — | — | EP | disclosed |
| CN-110959001-B | Method of making a chelant mixture, chelant mixture and method of using same | 凯米拉公司 | 2022-09-20 | — | — | CN | disclosed |