SCHEMBL6314684

SCHEMBL6314684

Nc1ccccc1N(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TSHR P16473 3/20 0.58
HSD17B10 Q99714 3/20 0.58
HPGD P15428 3/20 0.58
CYP3A4 P08684 2/20 0.58
KEAP1 Q14145 1/20 0.58
TDP1 Q9NUW8 2/20 0.48
SIGMAR1 Q99720 7/20 0.46
HPRT1 P00492 1/20 0.44
CHEK1 O14757 1/20 0.39
NEK2 P51955 1/20 0.39
LIMK1 P53667 1/20 0.39
DYRK1A Q13627 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
PLAU P00749 1/20 0.39
PLAT P00750 1/20 0.39
KLK1 P06870 1/20 0.39
PRSS1 P07477 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15561429 0.89 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL516020 0.87 SIGMAR1 (0.56) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL29870751 0.87 SIGMAR1 (0.56) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL6568773 0.87 SIGMAR1 (0.56) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL11238026 0.82 CYP3A4 (0.53) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL5146946 0.79 CYP3A4 (0.50) ALDH1A1TSHRHSD17B10HPGDCYP3A4
Boric Acid SCHEMBL29084632 0.78 SIGMAR1 (0.53) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL9934401 0.77 SIGMAR1 (0.50) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL29627309 0.77 SIGMAR1 (0.47) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL788000 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10HPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113165356-B Multilayer sheet and transfer material 哈利玛化成株式会社 2023-12-26 CN disclosed
WO-2020116234-A1 MOLD RESIN WITH ATTACHED HARD COAT LAYER, AND METHOD FOR PRODUCING SAME ハリマ化成株式会社 2020-06-11 WO disclosed
US-6914098-B2 Acrylic elastomer and its composition NIPPON MEKIRON, LIMITED (JP) 2005-07-05 US disclosed
EP-0905163-B1 Acrylic elastomer composition NIPPON MEKTRON KK (JP) 2004-10-27 EP disclosed
US-20040087729-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-05-06 US disclosed
US-20040019154-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-01-29 US disclosed
US-20010005742-A1 Acrylic elastomer and its composition NIPPON MEKTRON, LIMITED 2001-06-28 US disclosed
EP-1110980-A1 Acrylic elastomer and its composition Nippon Mektron, Limited (JP) 2001-06-27 EP disclosed
US-6015860-A POLYFUNCTIONAL (BLOCKED) ISOCYANATE, GUANIDINE, QUATERNARY AMMONIUM SALT, TERTIARY AMINE, AND TERTIARY PHOSPHINE VULCANIZATION ACCELERATOR; HEAT AND SCORCH RESISTANCE; RESILIENCE NIPPON MEKTRON, LIMITED (JP) 2000-01-18 US disclosed
EP-0905163-A1 Acrylic elastomer composition Nippon Mektron, Limited (JP) 1999-03-31 EP disclosed