Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 6/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969535 | 1.00 | HTR1B (0.48) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL827493 | 0.92 | HTR1B (0.47) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL23412378 | 0.89 | MAPT (0.52) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL10950611 | 0.89 | NCF1 (0.51) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL10945765 | 0.89 | NCF1 (0.51) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL19938062 | 0.88 | TLR8 (0.47) | HTR1AMEN1KMT2ANCF1TLR8 | |
| SCHEMBL23412188 | 0.87 | NCF1 (0.51) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL23412437 | 0.86 | NCF1 (0.58) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL9601934 | 0.86 | SYK (0.54) | HTR1BHTR1AHTR1DMEN1KMT2A | |
| SCHEMBL23412394 | 0.84 | NCF1 (0.59) | KDM4EMAPTNCF1CYBBNOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257540-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | ANHUI RONGHANG BIOTECH DEVELOPMENT CO., LTD. (CN) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257540-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HEPATITIS B VIRUS INFECTION | ABCB1, CYP7A1, CYP3A43 | HTR1B 2192/4885HTR1A 3678/4885HTR1D 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.