Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.70 |
| ▸ | ACACA | Q13085 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mangiferonic Acid SCHEMBL30415919 | 1.00 | ACLY (0.70) | ACLYACACAMAPK1HSD11B1MEN1 | |
| Cycloartenone SCHEMBL29504219 | 0.90 | HSD11B1 (0.61) | ACLYACACAMAPK1HSD11B1MEN1 | |
| SCHEMBL29934719 | 0.84 | PTPN11 (0.71) | ACLYACACAMAPK1HSD11B1MEN1 | |
| Isomangiferolic Acid SCHEMBL30515225 | 0.83 | ACLY (1.00) | ACLYACACAMAPK1HSD11B1MEN1 | |
| Mangiferolic Acid SCHEMBL17057008 | 0.83 | ACLY (1.00) | ACLYACACAMAPK1HSD11B1MEN1 | |
| Mangiferolic Acid SCHEMBL31097460 | 0.83 | ACLY (1.00) | ACLYACACAMAPK1HSD11B1MEN1 | |
| SCHEMBL5824245 | 0.82 | HSD11B1 (0.69) | ACLYACACAMAPK1HSD11B1MEN1 | |
| SCHEMBL29934767 | 0.80 | HSD11B1 (0.77) | ACLYACACAMAPK1HSD11B1MEN1 | |
| Vaticinone SCHEMBL29670808 | 0.80 | HSD11B1 (0.60) | ACLYACACAMAPK1HSD11B1MEN1 | |
| SCHEMBL31237297 | 0.80 | HSD11B1 (0.82) | ACLYACACAMAPK1HSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427595-B2 | Compositions and methods for inhibiting viral infection | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427595-B2 | Compositions and methods for inhibiting viral infection | HAVCR2, MAVS, EIF2AK2 | ACLY 2065/4885ACACA 559/4885MAPK1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.