Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.63 |
| ▸ | MELK | Q14680 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23250027 | 1.00 | BCL6 (0.63) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267872 | 0.93 | BCL6 (0.64) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL29874209 | 0.89 | BCL6 (0.67) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23250073 | 0.89 | BCL6 (0.67) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL31554644 | 0.85 | BCL6 (0.68) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267604 | 0.85 | BCL6 (0.70) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284344 | 0.85 | BCL6 (0.70) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL30706138 | 0.85 | BCL6 (0.71) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23249905 | 0.84 | BCL6 (0.64) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL29874020 | 0.84 | BCL6 (0.64) | BCL6NCOR2MELKCHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019369-A | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115397821-B | Bifunctional molecules comprising an E3 ubiquitin ligase binding moiety linked to a BCL6 targeting moiety | 阿尔维纳斯运营股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4045496-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | Arvinas Operations, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |