Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735718 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL4131823 | 0.88 | ATM (0.47) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL15270721 | 0.86 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL14565801 | 0.86 | LMNA (0.52) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL31085599 | 0.86 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL31085600 | 0.86 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL28372965 | 0.85 | LMNA (0.49) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL16412469 | 0.84 | PDGFRB (0.57) | ALDH1A1MEN1KMT2AGAAGFER | |
| SCHEMBL31170840 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAGFERPDGFRB | |
| SCHEMBL286994 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAGFERPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |