Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275378 | 1.00 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| Formaldehyde SCHEMBL28073057 | 0.94 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| Toluene SCHEMBL28185032 | 0.87 | MAOA (0.40) | MAOAFTOMAOBHPGDHSD17B10 | |
| 1-Naphthol SCHEMBL17580890 | 0.76 | CYP1A2 (0.63) | MAOAFTOMAOBHPGDHSD17B10 | |
| 1-Naphthol SCHEMBL29215642 | 0.76 | CYP1A2 (0.63) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL13947728 | 0.73 | MAOA (0.46) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL19354174 | 0.73 | MAOA (0.42) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL824913 | 0.71 | CYP3A4 (0.48) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL289214 | 0.71 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL275377 | 0.71 | MAOA (0.50) | MAOAFTOMAOBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| WO-2022213932-A1 | PYRROLOPYRIMIDINONE COMPOUND AND APPLICATION THEREOF | 广州必贝特医药股份有限公司 | 2022-10-13 | — | — | WO | disclosed |