Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875889 | 1.00 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| Formaldehyde SCHEMBL28073057 | 0.94 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| Toluene SCHEMBL28185032 | 0.87 | MAOA (0.40) | MAOAFTOMAOBHPGDHSD17B10 | |
| 1-Naphthol SCHEMBL17580890 | 0.76 | CYP1A2 (0.63) | MAOAFTOMAOBHPGDHSD17B10 | |
| 1-Naphthol SCHEMBL29215642 | 0.76 | CYP1A2 (0.63) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL13947728 | 0.73 | MAOA (0.46) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL19354174 | 0.73 | MAOA (0.42) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL824913 | 0.71 | CYP3A4 (0.48) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL289214 | 0.71 | MAOA (0.45) | MAOAFTOMAOBHPGDHSD17B10 | |
| SCHEMBL275377 | 0.71 | MAOA (0.50) | MAOAFTOMAOBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | claimed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| CN-116554189-A | Efficient preparation method of isopsoralen | 河南中烟工业有限责任公司 | 2023-08-08 | — | — | CN | claimed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | claimed |
| US-12570643-B2 | 3-aryloxy-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2026-03-10 | — | — | US | disclosed |
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12354864-B2 | Biomarkers and uses thereof | THE UNIVERSITY OF MANCHESTER (GB) | 2025-07-08 | — | — | US | disclosed |
| EP-3838900-B1 | 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF | ZHANGZHOU PIEN TZE HUANG PHARM (CN) | 2025-02-12 | — | — | EP | disclosed |
| US-20250042884-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2025-02-06 | — | — | US | disclosed |
| US-12139476-B2 | 3-aryloxyl-3-five-membered heteroaryl propylamine compound and use thereof | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2024-11-12 | — | — | US | disclosed |
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-13 | — | — | US | disclosed |
| EP-0399773-A1 | Novel 7-aroyl-4-hydroxy-3-methyl benzolfurans as dual inhibitors of cyclooxygenase and 5-lipoxygenase | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0054924-B1 | PHARMACEUTICAL COMPOUNDS, THEIR PREPARATION AND USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| US-4576632-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4535183-A | PALLIATION OF SICKLE CELL ANEMIA, RESPIRATORY DISORDERS, HYPOXIA, RADIOSENSITIZATION OF TUMORS | BURROUGHS WELLCOME CO. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4494979-A | HERBICIDES;PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0071441-A2 | Benzofuran sulfamates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0054924-A2 | Pharmaceutical compounds, their preparation and use | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-06-30 | — | — | EP | disclosed |
| US-3965182-A | Preparation of aniline from phenol and ammonia | ETHYL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | F2, F2RL3, F12 | MAOA 295/4885FTO 4722/4885MAOB 507/4885 |
| US-12139476-B2 | 3-aryloxyl-3-five-membered heteroaryl propylamine compound and use thereof | TRPV1, TRPA1, TRPM5 | MAOA 1933/4885FTO 2696/4885MAOB 2212/4885 |
| US-12570643-B2 | 3-aryloxy-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof | TRPA1, TRPM7, TRPV1 | MAOA 1957/4885FTO 3013/4885MAOB 2672/4885 |
| US-20250042884-A1 | 3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF | TRPV1, TRPA1, TRPM5 | MAOA 1933/4885FTO 2696/4885MAOB 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.