Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29881017 | 1.00 | NR1H4 (0.56) | NR1H4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL29880929 | 0.89 | ALDH1A1 (0.46) | NR1H4KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL29881661 | 0.89 | ALDH1A1 (0.47) | NR1H4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL29880945 | 0.88 | KDM4E (0.50) | NR1H4KDM4ELMNARAB9ANPC1 | |
| Cyclohexane Carboxamide SCHEMBL28819611 | 0.88 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL29881223 | 0.87 | PTGER4 (0.45) | NR1H4KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL29881716 | 0.87 | KDM4E (0.44) | NR1H4KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL29880939 | 0.83 | MAPK10 (0.48) | NR1H4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL3573274 | 0.81 | NR1H4 (0.85) | NR1H4 | |
| SCHEMBL3568478 | 0.81 | NR1H4 (0.85) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |