Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29880945 | 0.89 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29881017 | 0.89 | NR1H4 (0.56) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29880832 | 0.89 | NR1H4 (0.56) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29881716 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29881223 | 0.88 | PTGER4 (0.45) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29880939 | 0.88 | MAPK10 (0.48) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| Cyclohexane Carboxamide SCHEMBL28819590 | 0.87 | NR1H4 (0.49) | NR1H4PDE6D | |
| Cyclohexane Carboxamide SCHEMBL28819682 | 0.87 | NR1H4 (0.49) | NR1H4PDE6D | |
| SCHEMBL29881661 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL29880909 | 0.82 | PTGS2 (0.46) | ALDH1A1KDM4EHSD17B10LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |