Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29880929 | 0.89 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| Cyclohexane Carboxamide SCHEMBL28819715 | 0.88 | NR1H4 (0.49) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29880832 | 0.88 | NR1H4 (0.56) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29881017 | 0.88 | NR1H4 (0.56) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29881716 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29881223 | 0.87 | PTGER4 (0.45) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29880939 | 0.83 | MAPK10 (0.48) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29881661 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1RAB9AHSD17B10TP53 | |
| SCHEMBL3571322 | 0.81 | NR1H4 (0.71) | MAPTLMNANR1H4 | |
| SCHEMBL29880909 | 0.81 | PTGS2 (0.46) | KDM4EALDH1A1HPGDRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |