Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884195 | 1.00 | GAA (0.54) | GAARAPGEF4MEN1KMT2AHTT | |
| SCHEMBL2426442 | 0.84 | TRPV4 (0.42) | GAAKMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29627448 | 0.84 | TRPV4 (0.42) | GAAKMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL2865420 | 0.83 | GAA (0.56) | GAARAPGEF4MEN1KMT2AHTT | |
| SCHEMBL11496596 | 0.81 | CA2 (0.55) | GAARAPGEF4MEN1KMT2AL3MBTL1 | |
| SCHEMBL7146564 | 0.81 | GAA (0.54) | GAARAPGEF4MEN1KMT2AHTT | |
| Potassium Ion SCHEMBL2503311 | 0.80 | GAA (0.52) | GAARAPGEF4MEN1KMT2AHTT | |
| SCHEMBL6142648 | 0.79 | GAA (0.56) | GAARAPGEF4MEN1KMT2AHTT | |
| SCHEMBL11127859 | 0.79 | GAA (0.60) | GAARAPGEF4MEN1KMT2AHTT | |
| SCHEMBL11179994 | 0.79 | RAPGEF4 (0.62) | GAARAPGEF4MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344287-B | Novel substituted biaryl compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors | 默沙东有限责任公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-4048397-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents Of The University Of Michigan (US) | 2022-08-31 | — | — | EP | disclosed |