SCHEMBL2988147

SCHEMBL2988147

c1ccc2sc(B3OCCCO3)cc2c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.41
ASIC3 Q9UHC3 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
SIGMAR1 Q99720 8/20 0.39
AGXT P21549 1/20 0.38
ADRB2 P07550 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MGLL Q99685 1/20 0.37
BCL2L1 Q07817 1/20 0.36
CA2 P00918 1/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
THPO P40225 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2473736 0.80 CYP2A6 (0.47) CYP2A6ASIC3LOXL2SIGMAR1AGXT
SCHEMBL119228 0.72 LPL (0.44) CYP2A6ASIC3LOXL2SIGMAR1AGXT
SCHEMBL4258467 0.71
SCHEMBL7214928 0.69 LPL (0.40) CYP2A6CA2CYP3A4
SCHEMBL14983483 0.68 ALDH1A1 (0.36) CYP3A4
SCHEMBL13136869 0.65
SCHEMBL11958367 0.64 HTT (0.32)
SCHEMBL18124824 0.64 CA1 (0.39) CA2
SCHEMBL14983522 0.63 TRPM4 (0.38) CYP2A6L3MBTL1CYP2D6TSHRCYP2C19
SCHEMBL1136933 0.62 LPL (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781761-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-24 US disclosed
US-7781761-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-24 US disclosed
US-7781761-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-24 US disclosed
US-20080210933-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-04 US disclosed
US-20080210933-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-04 US disclosed
US-20080210933-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-04 US disclosed
US-7355199-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-08 US disclosed
US-7355199-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-08 US disclosed
US-20060131570-A1 Substituted anthracenes and electronic devices containing the substituted anthracenes E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-22 US disclosed
WO-2006050496-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-11 WO disclosed