Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988268 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2ATSHRMEN1KCNQ4 | |
| SCHEMBL13247945 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2ATSHRMEN1KCNQ4 | |
| SCHEMBL2516499 | 0.86 | CYP17A1 (0.43) | KMT2AKCNQ4KCNQ5CYP17A1BRAF | |
| SCHEMBL13345937 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KMT2ATSHRMEN1HPGD | |
| SCHEMBL2999891 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ATSHRMEN1HPGD | |
| SCHEMBL2999895 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ATSHRMEN1HPGD | |
| SCHEMBL13247959 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ATSHRMEN1HPGD | |
| SCHEMBL13247975 | 0.83 | HRH3 (0.47) | ALDH1A1TSHRNPC1GAA | |
| SCHEMBL13247944 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2ATSHRMEN1HPGD | |
| SCHEMBL13247957 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2ATSHRMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184813-A1 | CHEMICAL COMPOUNDS 553 | ASTRAZENECA AB (SE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184813-A1 | CHEMICAL COMPOUNDS 553 | GCGR, DGAT1, GPBAR1 | ALDH1A1 559/4885KMT2A 1048/4885TSHR 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.