Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456530 | 1.00 | OPRD1 (0.50) | OPRD1OPRM1MMESLC6A2CTSC | |
| SCHEMBL30746746 | 0.98 | OPRD1 (0.49) | OPRD1OPRM1MMESLC6A2CTSC | |
| SCHEMBL31453800 | 0.92 | OPRM1 (0.40) | OPRD1OPRM1MMESLC6A2ECE1 | |
| SCHEMBL30254475 | 0.90 | OPRM1 (0.39) | OPRD1OPRM1MMESLC6A2ECE1 | |
| SCHEMBL31063872 | 0.90 | OPRD1 (0.44) | OPRD1OPRM1OPRK1BACE1 | |
| SCHEMBL30799513 | 0.89 | BACE1 (0.49) | OPRD1OPRM1MMEBACE1 | |
| SCHEMBL30009160 | 0.88 | CALCRL (0.48) | OPRD1OPRM1OPRK1BACE1 | |
| SCHEMBL31039959 | 0.88 | MME (0.45) | OPRD1OPRM1MMESLC6A2 | |
| SCHEMBL31259942 | 0.88 | MME (0.47) | MMEGNPAT | |
| SCHEMBL30578424 | 0.88 | MME (0.47) | MMEGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310727-B | Conditionally active heterodimeric polypeptides and methods of use thereof | 加利福尼亚大学董事会 | 2022-09-27 | — | — | CN | disclosed |