SCHEMBL30254475

SCHEMBL30254475

C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 3/20 0.39
▸ OPRD1 P41143 3/20 0.39
▸ MME P08473 4/20 0.38
▸ SLC6A2 P23975 1/20 0.35
▸ PDCD1LG2 Q9BQ51 1/20 0.34
▸ CD274 Q9NZQ7 1/20 0.34
▸ MAGI3 Q5TCQ9 1/20 0.34
▸ FNTA P49354 4/20 0.33
▸ FNTB P49356 4/20 0.33
▸ BACE1 P56817 1/20 0.33
▸ ECE1 P42892 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31453800 0.98 OPRM1 (0.40) OPRM1OPRD1MMESLC6A2PDCD1LG2
SCHEMBL31391114 0.94 SLC6A2 (0.36) OPRM1OPRD1MMESLC6A2FNTA
SCHEMBL8527609 0.92 MME (0.43) OPRM1OPRD1MMEPDCD1LG2CD274
SCHEMBL8527615 0.92 MME (0.43) OPRM1OPRD1MMEPDCD1LG2CD274
SCHEMBL29961849 0.92 MME (0.43) OPRM1OPRD1MMEPDCD1LG2CD274
SCHEMBL30746746 0.92 OPRD1 (0.49) OPRM1OPRD1MMESLC6A2BACE1
SCHEMBL29590364 0.92 OPRM1 (0.39) OPRM1OPRD1SLC6A2MAGI3FNTA
SCHEMBL30974040 0.92 OPRM1 (0.42) OPRM1OPRD1MMEPDCD1LG2CD274
Water SCHEMBL29655402 0.91 MME (0.43) OPRM1OPRD1MMEPDCD1LG2CD274
SCHEMBL30997434 0.91 MME (0.38) OPRM1OPRD1MMEPDCD1LG2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720873-B1 GLUCAGON-LIKE PEPTIDES IP2IPO INNOVATIONS LTD (GB) 2024-12-04 — — EP claimed
US-11591380-B2 Glucagon-like peptides IP2IPO INNOVATIONS LIMITED (GB) 2023-02-28 — — US claimed
EP-3720873-B1 GLUCAGON-LIKE PEPTIDES IP2IPO INNOVATIONS LTD (GB) 2024-12-04 — — EP disclosed
US-11591380-B2 Glucagon-like peptides IP2IPO INNOVATIONS LIMITED (GB) 2023-02-28 — — US disclosed
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