Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692155 | 0.84 | LMNA (0.52) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL29883887 | 0.84 | PDE2A (0.43) | LMNATSHRALDH1A1HSD17B10ADRA2A | |
| SCHEMBL24298707 | 0.83 | KDM4E (0.57) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL29059329 | 0.83 | KDM4E (0.57) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL24298148 | 0.83 | KDM4E (0.57) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL29059332 | 0.83 | KDM4E (0.57) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL7813248 | 0.83 | SLC6A2 (0.40) | TSHR | |
| SCHEMBL30620725 | 0.79 | CES2 (0.47) | PDE2A | |
| SCHEMBL18290609 | 0.78 | LMNA (0.46) | SLC22A2SLC22A1SLC22A3LMNATYR | |
| SCHEMBL18291827 | 0.78 | LMNA (0.46) | SLC22A2SLC22A1SLC22A3LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947839-A | Amino alcohol compound, oxazoline compound, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2023-10-27 | — | — | CN | disclosed |
| CN-115108874-B | Amine azide chiral compound, bis-azide chiral compound and related preparation methods | 中国科学院福建物质结构研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-115108874-A | Amine azide chiral compound, bis-azide chiral compound and related preparation methods | 中国科学院福建物质结构研究所 | 2022-09-27 | — | — | CN | disclosed |