SCHEMBL3692155

SCHEMBL3692155

CC(C)(C)c1ccc(C(O)C(O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 2/20 0.48
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
NR1H4 Q96RI1 2/20 0.42
HDAC1 Q13547 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GRIA4 P48058 2/20 0.40
SRD5A2 P31213 1/20 0.40
GRIN2B Q13224 1/20 0.40
KIF11 P52732 1/20 0.39
CYP1A2 P05177 1/20 0.39
FFAR1 O14842 1/20 0.39
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18291827 0.88 LMNA (0.46) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL6055096 0.88 LMNA (0.46) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL18290609 0.88 LMNA (0.46) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL11841795 0.86 LMNA (0.44) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL24298148 0.84 KDM4E (0.57) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL29059329 0.84 KDM4E (0.57) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL29059332 0.84 KDM4E (0.57) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL24298707 0.84 KDM4E (0.57) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL29883290 0.84 SLC22A2 (0.44) LMNATYRTSHRALDH1A1HSD17B10
SCHEMBL11845496 0.84 LMNA (0.43) LMNATYRTSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067761-B1 METHOD OF PRODUCING DIOL, POLYDIOL, SECONDARY ALCOHOL OR DIKETONE COMPOUND JAPAN SCIENCE & TECH AGENCY (JP) 2015-07-08 EP disclosed
US-7696386-B2 Method of producing diol, polydiol, secondary alcohol or diketone compound JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-04-13 US disclosed
US-20090240085-A1 METHOD OF PRODUCING DIOL, POLYDIOL, SECONDARY ALCOHOL OR DIKETONE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-09-24 US disclosed
EP-2067761-A1 METHOD OF PRODUCING DIOL, POLYDIOL, SECONDARY ALCOHOL OR DIKETONE COMPOUND Japan Science and Technology Agency (JP) 2009-06-10 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240085-A1 METHOD OF PRODUCING DIOL, POLYDIOL, SECONDARY ALCOHOL OR DIKETONE COMPOUND HSD17B7, ADH1C, DHCR7 LMNA 2849/4885TYR 4014/4885TSHR 4680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.