⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317599 | 0.72 | MAPT (0.37) | — | |
| SCHEMBL16433204 | 0.72 | AXL (0.38) | — | |
| SCHEMBL30317483 | 0.66 | TP53 (0.40) | — | |
| SCHEMBL30754597 | 0.63 | PTGS2 (0.31) | — | |
| SCHEMBL4540326 | 0.62 | MAPT (0.61) | — | |
| SCHEMBL29633340 | 0.62 | MAPT (0.61) | — | |
| SCHEMBL30594079 | 0.62 | MAPT (0.63) | — | |
| SCHEMBL11658096 | 0.60 | DNM1 (0.37) | — | |
| Mansouramycin B SCHEMBL29886187 | 0.58 | MAPT (0.36) | — | |
| SCHEMBL359515 | 0.58 | MAPT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |