Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558105 | 0.96 | CDC7 (0.46) | CDC7GSK3BABCB1GCGRALDH1A1 | |
| SCHEMBL954434 | 0.95 | ABCB1 (0.41) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL64690 | 0.94 | ABCB1 (0.42) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL12293879 | 0.94 | ABCB1 (0.42) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL19206652 | 0.93 | CDC7 (0.45) | CDC7GSK3BALDH1A1ADORA3LTB4R | |
| SCHEMBL2680751 | 0.92 | ABCB1 (0.40) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL10196941 | 0.89 | ABCB1 (0.39) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL20841749 | 0.89 | ABCB1 (0.39) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL20841761 | 0.89 | ABCB1 (0.39) | CDC7ABCB1ALDH1A1ADORA3ADORA1 | |
| SCHEMBL10196910 | 0.89 | PARP1 (0.38) | CDC7ABCB1ALDH1A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | UNIV VIRGINIA PATENT FOUNDATION (US) | 2026-03-19 | — | — | US | disclosed |
| US-20220259574-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | KCNN2, KCNN1, ATP1B2 | CDC7 2006/4885GSK3B 1789/4885ABCB1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.