Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D known ✓ | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B known ✓ | P35368 | 2/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19745058 | 0.98 | NCF1 (0.56) | NCF1LOXL2CCR1CCR5CCR8 | |
| SCHEMBL9815408 | 0.98 | NCF1 (0.56) | NCF1LOXL2CCR1CCR5CCR8 | |
| SCHEMBL31559 | 0.98 | NCF1 (0.56) | NCF1LOXL2CCR1CCR5CCR8 | |
| SCHEMBL29578471 | 0.98 | NCF1 (0.56) | NCF1LOXL2CCR1CCR5CCR8 | |
| Iodide SCHEMBL23391640 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 | |
| Water SCHEMBL2007545 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL11672468 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL30800448 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 | |
| Charcoal, Activated SCHEMBL30167892 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 | |
| SCHEMBL29712077 | 0.95 | NCF1 (0.54) | NCF1LOXL2CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737898-A2 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP Biotech GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| US-20260042797-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2026-02-12 | — | — | US | disclosed |
| US-12344633-B2 | Separation and isolation of nucleic acids using affinity ligands bound to a solid surface | EMP BIOTECH GMBH (DE) | 2025-07-01 | — | — | US | disclosed |
| EP-4065591-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP Biotech GmbH (DE) | 2022-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344633-B2 | Separation and isolation of nucleic acids using affinity ligands bound to a solid surface | ADAR, SSBP1, POLRMT | HTR1A 3044/4885ADRA1D 4276/4885ADRA1A 3615/4885 |
| US-20260042797-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | POLM, SSBP1, POLRMT | HTR1A 2390/4885ADRA1D 2009/4885ADRA1A 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.