Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | PRKDC | P78527 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29887322 | 0.83 | HTR3A (0.53) | NPC1RAB9AKDM4EMAPTAHR | |
| SCHEMBL1938064 | 0.82 | SLC16A3 (0.51) | PRKDCACEECE1NPC1RAB9A | |
| SCHEMBL19642427 | 0.78 | MAOA (0.55) | PRKDCNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL2400184 | 0.77 | PRKDC (0.51) | PRKDCNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14802157 | 0.74 | PRKDC (0.50) | TSHRPRKDCACEECE1NPC1 | |
| SCHEMBL5454434 | 0.74 | MGAM (0.63) | PRKDCACEECE1ALDH1A1KDM4E | |
| SCHEMBL22742604 | 0.73 | MAPT (0.57) | TSHRPRKDCNPC1RAB9AALDH1A1 | |
| SCHEMBL22741398 | 0.73 | MAPT (0.57) | TSHRPRKDCNPC1RAB9AALDH1A1 | |
| SCHEMBL29886896 | 0.73 | CHRNA7 (0.54) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24270394 | 0.73 | KDM4E (0.60) | PRKDCALDH1A1TP53KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |