Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811542 | 1.00 | EED (0.56) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3958847 | 0.90 | GBA1 (0.62) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21892421 | 0.81 | CXCR4 (0.53) | SLC6A2SLC6A4SLC6A3HTR2CHTR6 | |
| SCHEMBL23886405 | 0.81 | TAAR1 (0.48) | POLB | |
| SCHEMBL29889395 | 0.81 | EED (0.52) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13739140 | 0.81 | EED (0.52) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13740423 | 0.81 | EED (0.52) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22265953 | 0.81 | EED (0.52) | EEDGBA1SLC6A4HTR2CHTR6 | |
| SCHEMBL1812734 | 0.81 | EED (0.52) | EEDGBA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29890848 | 0.81 | EED (0.52) | EEDGBA1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336991-B2 | Factor XIIA inhibitors | UNIVERSITY OF LEEDS (GB) | 2025-06-24 | — | — | US | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | EED 3279/4885GBA1 536/4885SLC6A2 4224/4885 |
| US-12336991-B2 | Factor XIIA inhibitors | F11, F13B, F12 | EED 3279/4885GBA1 536/4885SLC6A2 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.