Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196191 | 0.78 | KEAP1 (0.33) | KEAP1NFE2L2 | |
| SCHEMBL1260690 | 0.76 | KEAP1 (0.33) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL1072250 | 0.75 | ALDH1A1 (0.33) | KEAP1NFE2L2EPHX1SSTR4 | |
| SCHEMBL9067197 | 0.73 | ALDH1A1 (0.35) | EPHX1 | |
| SCHEMBL6255794 | 0.70 | KEAP1 (0.41) | KEAP1NFE2L2EPHX1SSTR4CHRM3 | |
| SCHEMBL4728809 | 0.70 | KEAP1 (0.41) | KEAP1NFE2L2EPHX1SSTR4CHRM3 | |
| SCHEMBL11814849 | 0.70 | KEAP1 (0.41) | KEAP1NFE2L2EPHX1SSTR4CHRM3 | |
| SCHEMBL28730098 | 0.69 | KEAP1 (0.44) | KEAP1NFE2L2EPHX1SSTR4CHRM3 | |
| SCHEMBL29122810 | 0.69 | EPHX1 (0.39) | KEAP1NFE2L2EPHX1SSTR4CHRM3 | |
| SCHEMBL1876976 | 0.69 | EPHX1 (0.39) | KEAP1NFE2L2EPHX1SSTR4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267251-A1 | CYCLIC PEPTIDES AND USES THEREOF | Preveceutical Medical Inc. (CA) | 2023-11-01 | — | — | EP | disclosed |
| EP-4175970-A1 | PEPTIDES AND USES THEREOF | Preveceutical Medical Inc. (CA) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022133540-A1 | CYCLIC PEPTIDES AND USES THEREOF | PreveCeutical Medical Inc. (CA) | 2022-06-30 | — | — | WO | disclosed |