Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 2/20 | 0.54 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.54 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.54 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.54 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.54 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.54 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.54 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904505 | 0.85 | FBP1 (0.61) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL4909482 | 0.85 | FBP1 (0.61) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29843061 | 0.84 | APP (0.52) | APPABCG2GAAKDM4EMAPT | |
| SCHEMBL31438664 | 0.82 | ABCG2 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL5569925 | 0.82 | ABCG2 (0.68) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL34972 | 0.81 | TERT (0.76) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL31682973 | 0.81 | TERT (0.76) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL12639988 | 0.79 | MEN1 (0.61) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL25300326 | 0.75 | MEN1 (0.73) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL21668590 | 0.75 | CDK2 (0.54) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200542-A1 | FLAVONOID POLYAMINES AND THEIR USE TREATING CENTRAL NERVOUS SYSTEM DISORDERS | Floratek Pharma SA (CH) | 2022-09-29 | — | — | WO | disclosed |