SCHEMBL34972

SCHEMBL34972

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(O)c(O)ccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.76
▸ APP P05067 2/20 0.71
▸ KDM4E B2RXH2 3/20 0.67
▸ MEN1 O00255 3/20 0.67
▸ MAPT P10636 3/20 0.67
▸ ALOX15 P16050 3/20 0.67
▸ KMT2A Q03164 3/20 0.67
▸ SLCO2B1 O94956 2/20 0.67
▸ ALDH1A1 P00352 2/20 0.67
▸ HPGD P15428 2/20 0.67
▸ APEX1 P27695 2/20 0.67
▸ GLA P06280 1/20 0.67
▸ FBP1 P09467 1/20 0.67
▸ HSPD1 P10809 1/20 0.67
▸ CYP19A1 P11511 1/20 0.67
▸ RAD52 P43351 1/20 0.67
▸ DAPK1 P53355 1/20 0.67
▸ HSPE1 P61604 1/20 0.67
▸ TST Q16762 1/20 0.67
▸ CDK2 P24941 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682973 1.00 TERT (0.76) TERTAPPKDM4EMEN1MAPT
SCHEMBL12639988 0.89 MEN1 (0.61) TERTAPPKDM4EMEN1MAPT
SCHEMBL6614041 0.87 TERT (1.00) TERTAPPKDM4EMEN1MAPT
SCHEMBL6616091 0.87 TERT (1.00) TERTAPPKDM4EMEN1MAPT
SCHEMBL29904505 0.86 FBP1 (0.61) TERTAPPKDM4EMEN1MAPT
SCHEMBL4909482 0.86 FBP1 (0.61) TERTAPPKDM4EMEN1MAPT
SCHEMBL7655891 0.85 APP (0.67) TERTAPPKDM4EMEN1MAPT
SCHEMBL34929 0.85 APP (0.67) TERTAPPKDM4EMEN1MAPT
SCHEMBL7661955 0.85 CDK2 (0.68) TERTAPPKDM4EMEN1MAPT
SCHEMBL14697063 0.83 ABCG2 (0.73) TERTAPPKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US claimed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US claimed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US claimed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US claimed
EP-1109800-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LIMITED (KR) 2001-06-27 — — EP claimed
WO-2000012496-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LTD. (KR) 2000-03-09 — — WO claimed
US-20250281560-A1 METHOD FOR PREVENTING AND/OR TREATING CANCER OR AUTOIMMUNE DISEASE WITH 3,4,2 Prime,3 Prime,4 Prime-PENTAHYDROXY-TRANS-CHALCONE NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-09-11 — — US disclosed
CN-115612699-B Copolymer membrane, and enzymatic self-assembly synthesis method and application thereof in gas-liquid interface 中国科学院天津工业生物技术研究所 2024-10-25 — — CN disclosed
CN-115612114-B Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof 中国科学院天津工业生物技术研究所 2024-02-20 — — CN disclosed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 — — CN disclosed
WO-2023284777-A1 COPOLYMER FILM, ENZYME CATALYSIS SELF-ASSEMBLY SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院天津工业生物技术研究所 2023-01-19 — — WO disclosed
CN-115612403-A Self-assembly strong-adhesion copolymer film, film coating method and application 中国科学院天津工业生物技术研究所 2023-01-17 — — CN disclosed
CN-115612699-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof at gas-liquid interface 中国科学院天津工业生物技术研究所 2023-01-17 — — CN disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed
US-6500846-B1 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE LG CHEMICAL, LTD. (KR) 2002-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA TERT 2205/4885APP 2870/4885KDM4E 1981/4885
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, ACACA, ACAT1 TERT 2114/4885APP 2424/4885KDM4E 1895/4885
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA TERT 2205/4885APP 2870/4885KDM4E 1981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback