SCHEMBL2989151

SCHEMBL2989151

Cc1cc(N)cc(C)c1Oc1ccc(C(c2ccc(Oc3c(C)cc(N)cc3C)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
RAB9A P51151 5/20 0.40
MAPT P10636 5/20 0.40
NPC1 O15118 3/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
AR P10275 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
LMNA P02545 1/20 0.35
ATM Q13315 1/20 0.35
TEAD4 Q15561 1/20 0.35
POLB P06746 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648768 0.89 ALDH1A1 (0.46) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL28793438 0.84 ALDH1A1 (0.38) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL2999317 0.82 ALDH1A1 (0.50) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL21496204 0.82 RAB9A (0.36) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL2999316 0.81 ALDH1A1 (0.47) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL22966185 0.81 ALDH1A1 (0.61) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL2997814 0.81 RAB9A (0.46) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL21468659 0.81 AR (0.42) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL3000872 0.80 ALDH1A1 (0.54) ALDH1A1RAB9AMAPTNPC1HPGD
SCHEMBL1148576 0.80 GRIN2B (0.40) ALDH1A1RAB9AMAPTNPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111133032-B Polyimide, polyimide varnish, and polyimide film 三菱瓦斯化学株式会社 2022-07-19 CN disclosed
CN-111051384-B Polyimide, polyimide varnish, and polyimide film 三菱瓦斯化学株式会社 2022-06-28 CN disclosed
US-11261303-B2 Polyimide resin film and method for producing polyimide resin film MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-03-01 US disclosed
EP-3489284-B1 POLYIMIDE RESIN FILM AND METHOD FOR PRODUCING POLYIMIDE RESIN FILM MITSUBISHI GAS CHEMICAL CO (JP) 2021-06-09 EP disclosed
US-20190185631-A1 POLYIMIDE RESIN FILM AND METHOD FOR PRODUCING POLYIMIDE RESIN FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2019-06-20 US disclosed
EP-3489284-A1 POLYIMIDE RESIN FILM AND METHOD FOR PRODUCING POLYIMIDE RESIN FILM Mitsubishi Gas Chemical Company, Inc. (JP) 2019-05-29 EP disclosed
US-9193850-B2 Nanocomposite, process for preparing the same, and surface emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-24 US disclosed
US-20130037786-A1 NANOCOMPOSITE, PROCESS FOR PREPARING THE SAME, AND SURFACE EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-14 US disclosed
US-8357322-B2 Process and apparatus for production of colorless transparent resin film MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-22 US disclosed
EP-2147766-B1 PROCESS AND APPARATUS FOR PRODUCTION OF COLORLESS TRANSPARENT RESIN FILM MITSUBISHI GAS CHEMICAL CO (JP) 2012-08-01 EP disclosed
US-20100187719-A1 PROCESS AND APPARATUS FOR PRODUCTION OF COLORLESS TRANSPARENT RESIN FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-07-29 US disclosed
EP-2147766-A1 PROCESS AND APPARATUS FOR PRODUCTION OF COLORLESS TRANSPARENT RESIN FILM Mitsubishi Gas Chemical Company, Inc. (JP) 2010-01-27 EP disclosed