Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460054 | 0.79 | TDP1 (0.38) | TDP1ALOX15CYP3A4TSHRALDH1A1 | |
| SCHEMBL3065223 | 0.79 | TDP1 (0.50) | TDP1SMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL249418 | 0.78 | TDP1 (0.44) | FDPSTDP1ALOX15CYP3A4CASP1 | |
| SCHEMBL1224647 | 0.76 | TDP1 (0.34) | FDPSTDP1ALOX15CYP3A4CASP1 | |
| Hydrochloric Acid SCHEMBL7205319 | 0.76 | TDP1 (0.42) | FDPSTDP1ALOX15CYP3A4CASP1 | |
| SCHEMBL1823532 | 0.75 | TDP1 (0.40) | TDP1ALOX15CYP3A4CASP1CASP7 | |
| Ammonia Solution, Strong SCHEMBL7560640 | 0.75 | TDP1 (0.33) | FDPSTDP1ALOX15CYP3A4CASP1 | |
| SCHEMBL890397 | 0.74 | CYP3A4 (0.39) | FDPSTDP1ARALOX15CYP3A4 | |
| SCHEMBL4249599 | 0.73 | TDP1 (0.33) | TDP1TSHRALDH1A1HTT | |
| SCHEMBL2992110 | 0.73 | CYP3A4 (0.44) | FDPSTDP1ARALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41549-E1 | Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives | WELLA AG (DE) | 2010-08-24 | — | — | US | disclosed |
| EP-1493731-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives | Wella Aktiengesellschaft (DE) | 2005-01-05 | — | — | EP | disclosed |
| US-6689174-B2 | FOR OXIDATIVELY DYEING HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | CHASSOT LAURENT (CH) | 2002-11-14 | — | — | US | disclosed |
| EP-1226107-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2002018318-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | KRT18, KPNB1, VIM | FDPS 4267/4885TDP1 2966/4885AR 2124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.