SCHEMBL890397

SCHEMBL890397

Nc1ccccc1Cc1cccc(N)c1Cc1ccccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.39
ALOX15 P16050 2/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AR P10275 1/20 0.39
FDPS P14324 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
HSPA5 P11021 1/20 0.36
TSHR P16473 5/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KEAP1 Q14145 1/20 0.34
PIK3CA P42336 1/20 0.33
POLB P06746 1/20 0.33
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8098064 0.85 GABRA1 (0.40) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL36019 0.85 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29373097 0.85 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL17745127 0.85 GABRA1 (0.40) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL9719138 0.83 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrochloric Acid SCHEMBL11743462 0.83 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL1759362 0.83 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Ammonia Solution, Strong SCHEMBL9517239 0.83 CYP3A4 (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL9563230 0.82 ALDH1A1 (0.35) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL23496022 0.81 CYP3A4 (0.43) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943809-B2 Solvent resistant thin film composite membrane and its preparation KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-04-17 US claimed
US-20170065937-A1 SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2017-03-09 US claimed
US-5147553-A Separation of fluid mixture IONICS, INCORPORATED (US) 1992-09-15 US claimed
US-20240425448-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
EP-4431490-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2024-09-18 EP disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
CN-111183131-B Method for recovering organic amine 旭化成株式会社 2022-06-28 CN disclosed
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2021-12-02 US disclosed
EP-3860743-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME The Penn State Research Foundation (US) 2021-08-11 EP disclosed
WO-2020072594-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION (US) 2020-04-09 WO disclosed
EP-0441453-A2 Process for preparing thermoset composite articles SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-14 EP disclosed
EP-0406959-A2 Maleimide composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-01-09 EP disclosed
EP-0406959-A2 Maleimide composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-01-09 EP disclosed
EP-0268906-A2 Compatibilized blends of alpha, omega-alkylene glycols and polyether polyols and process for preparing the same THE DOW CHEMICAL COMPANY (US) 1988-06-01 EP disclosed
US-4585804-A INSULATION THE DOW CHEMICAL COMPANY (US) 1986-04-29 US disclosed
EP-0061201-A1 A process for preparing a rigid polyurethane foam and the foam produced by the process THE DOW CHEMICAL COMPANY (US) 1982-09-29 EP disclosed
EP-0001425-B1 SUPPORTED RUTHENIUM CATALYST, PROCESS FOR ITS PREPARATION, AND ITS USE AS A HYDROGENATION CATALYST BAYER AG (DE) 1980-08-20 EP disclosed
US-4186145-A Process for the hydrogenation of an aromatic amine and the supported ruthenium catalyst used in the process BAYER AKTIENGESELLSCHAFT (DE) 1980-01-29 US disclosed
EP-0001425-A1 Supported ruthenium catalyst, process for its preparation, and its use as a hydrogenation catalyst BAYER AG (DE) 1979-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CYP3A4 3165/4885ALOX15 313/4885CASP1 4467/4885
US-20240425448-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION IDH3A, CA7, C9 CYP3A4 182/4885ALOX15 1785/4885CASP1 112/4885
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CYP3A4 3165/4885ALOX15 313/4885CASP1 4467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.