Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 15/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27123389 | 0.89 | FFAR4 (0.38) | SMYD3FFAR4TNKSPARP1SOS1 | |
| SCHEMBL30014467 | 0.89 | FFAR4 (0.38) | SMYD3FFAR4TNKSPARP1SOS1 | |
| SCHEMBL29893498 | 0.89 | FFAR4 (0.45) | FFAR4SOS1 | |
| SCHEMBL27118484 | 0.89 | FFAR4 (0.45) | FFAR4SOS1 | |
| SCHEMBL30864049 | 0.87 | FFAR4 (0.40) | FFAR4SOS1 | |
| SCHEMBL30864018 | 0.86 | FFAR4 (0.41) | FFAR4SOS1 | |
| SCHEMBL30864092 | 0.85 | FFAR4 (0.39) | FFAR4SOS1 | |
| SCHEMBL30267230 | 0.85 | HTT (0.39) | DDB1CRBNFFAR4SOS1 | |
| SCHEMBL27121574 | 0.84 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL30267237 | 0.84 | LIPG (0.40) | SMYD3TNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232108-B | SOS1 degradation agent and preparation method and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-115232114-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232111-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232108-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |