Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27118484 | 0.95 | FFAR4 (0.45) | FFAR4AKR1C3DRD3MGLLSOS1 | |
| SCHEMBL29893498 | 0.95 | FFAR4 (0.45) | FFAR4AKR1C3DRD3MGLLSOS1 | |
| SCHEMBL30864092 | 0.91 | FFAR4 (0.39) | FFAR4DRD3MGLLSOS1 | |
| SCHEMBL27123389 | 0.90 | FFAR4 (0.38) | FFAR4DRD3SOS1KMT2A | |
| SCHEMBL30014467 | 0.90 | FFAR4 (0.38) | FFAR4DRD3SOS1KMT2A | |
| SCHEMBL30864018 | 0.89 | FFAR4 (0.41) | FFAR4DRD3MGLLSOS1 | |
| SCHEMBL30267230 | 0.87 | HTT (0.39) | FFAR4DRD3SOS1KMT2A | |
| SCHEMBL29892407 | 0.87 | DDB1 (0.40) | FFAR4SOS1 | |
| SCHEMBL27121574 | 0.86 | FFAR4 (0.40) | FFAR4DRD3MGLLKMT2A | |
| SCHEMBL30014595 | 0.86 | GABRD (0.37) | FFAR4SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |