Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 7/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795216 | 0.83 | DHODH (0.36) | DHODHTNKSPARP1TNKS2TRPV1 | |
| SCHEMBL26224291 | 0.78 | ADORA2A (0.66) | TNKSTNKS2KITADORA2ABTK | |
| SCHEMBL29986864 | 0.78 | ADORA2A (0.66) | TNKSTNKS2KITADORA2ABTK | |
| SCHEMBL12775436 | 0.74 | TRPA1 (0.40) | MAP4K4KMT2ATRPA1 | |
| SCHEMBL21141124 | 0.74 | KIT (0.70) | KITKMT2A | |
| SCHEMBL24795222 | 0.70 | TRPV1 (0.37) | TRPV1KITADORA2ABTK | |
| SCHEMBL24795831 | 0.70 | RXRA (0.38) | PARP1TRPV1KITADORA2ABTK | |
| SCHEMBL17666810 | 0.69 | ADORA2A (0.72) | KITADORA2AALDH1A1MAP4K4 | |
| SCHEMBL29986591 | 0.69 | ADORA2A (0.72) | KITADORA2AALDH1A1MAP4K4 | |
| SCHEMBL24795225 | 0.69 | TRPV1 (0.37) | PARP1TRPV1KITADORA2ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |