Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 12/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2305775 | 0.85 | KDM1A (0.46) | CYP11B1CYP11B2MEN1KMT2AKDM1A | |
| SCHEMBL29893953 | 0.84 | IRAK4 (0.44) | CYP11B1CYP11B2TRPV3CHRNA7KDM1A | |
| SCHEMBL29893637 | 0.84 | CYP11B1 (0.39) | CYP11B1CYP11B2TRPV3CHRNA7HDAC8 | |
| SCHEMBL14884989 | 0.81 | ACHE (0.43) | MEN1KMT2A | |
| SCHEMBL10287024 | 0.81 | ACHE (0.43) | MEN1KMT2A | |
| SCHEMBL3311055 | 0.81 | ACHE (0.43) | MEN1KMT2A | |
| SCHEMBL29893831 | 0.78 | CYP11B1 (0.35) | CYP11B1CYP11B2TRPV3CHRNA7HDAC8 | |
| SCHEMBL10286368 | 0.77 | RAB9A (0.40) | MEN1KMT2AMAOB | |
| SCHEMBL31598496 | 0.77 | RAB9A (0.40) | MEN1KMT2AMAOB | |
| SCHEMBL10287034 | 0.77 | CYP11B1 (0.38) | CYP11B1CYP11B2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |