SCHEMBL10286368

SCHEMBL10286368

OC1CCCCc2ccc(-c3ccccc3)nc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ACHE P22303 2/20 0.40
ADORA1 P30542 5/20 0.37
ADORA2A P29274 3/20 0.37
ADORA3 P0DMS8 2/20 0.37
IRAK4 Q9NWZ3 1/20 0.36
SRC P12931 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
NR3C1 P04150 1/20 0.34
KCNH2 Q12809 1/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31598496 1.00 RAB9A (0.40) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL10287024 0.95 ACHE (0.43) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL3311055 0.95 ACHE (0.43) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL14884989 0.95 ACHE (0.43) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL31598495 0.89 MEN1 (0.44) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL28524204 0.89 MEN1 (0.44) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL28524205 0.89 MEN1 (0.44) RAB9AMEN1KMT2AACHEADORA1
SCHEMBL29893246 0.77 CYP11B1 (0.50) MEN1KMT2AMAOB
SCHEMBL11519752 0.77 RAB9A (0.37) RAB9AMEN1KMT2AADORA1ADORA2A
SCHEMBL3311297 0.77 IRAK4 (0.46) RAB9AMEN1KMT2AADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
WO-2012001040-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES MSR1, DDT, MPO RAB9A 2972/4885MEN1 1975/4885KMT2A 1808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.