Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893280 | 0.84 | KIF11 (0.43) | TNKSTNKS2KDM4EKMT2AKIF11 | |
| SCHEMBL21644728 | 0.83 | CCR4 (0.45) | GPR84TNKSTNKS2KDM4EALDH1A1 | |
| SCHEMBL29118702 | 0.83 | HPGDS (0.44) | GPR84TNKSTNKS2AKT1AKT2 | |
| SCHEMBL20464228 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29894104 | 0.78 | KIF11 (0.42) | GPR84TNKSTNKS2AKT1AKT2 | |
| SCHEMBL29893363 | 0.78 | GPR84 (0.40) | GPR84TNKSTNKS2AKT1AKT2 | |
| SCHEMBL24287306 | 0.76 | CYP1A2 (0.44) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29516239 | 0.76 | CYP1A2 (0.44) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL19660532 | 0.75 | KDM4E (0.69) | TNKSTNKS2AKT1AKT2KDM4E | |
| SCHEMBL1906154 | 0.74 | KDM4E (0.51) | TNKSTNKS2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |