Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627235 | 1.00 | MAPT (0.52) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| Silver SCHEMBL9170884 | 0.98 | MAPT (0.51) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL9170890 | 0.98 | MAPT (0.51) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL10622774 | 0.87 | ALDH1A1 (0.48) | MAPTMAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| Silver SCHEMBL9170887 | 0.87 | MAPT (0.39) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| Silver SCHEMBL9167961 | 0.85 | ALDH1A1 (0.47) | MAPTMAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9167964 | 0.85 | ALDH1A1 (0.47) | MAPTMAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL5702820 | 0.80 | MAPT (0.45) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL3733557 | 0.78 | TXNRD1 (0.46) | MAPTMAPK1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL2919937 | 0.76 | CYP3A4 (0.50) | MAPTMAPK1TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343706-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S. A. (PL) | 2024-10-17 | — | — | US | disclosed |
| CN-115023419-A | Cereblon-bound piperidine-2, 6-diones and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343706-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CRBN, CDR2, DRD2 | MAPT 4380/4885MAPK1 4145/4885TDP1 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.