Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | APEX1 | P27695 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.64 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610367 | 1.00 | TDP1 (0.64) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL22920980 | 1.00 | TDP1 (0.64) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL2988507 | 1.00 | TDP1 (0.64) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL13698041 | 0.83 | CYP3A4 (0.47) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL12916560 | 0.83 | TRPA1 (0.59) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL8848145 | 0.83 | TDP1 (0.60) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL13746777 | 0.82 | ALDH1A1 (0.68) | TDP1MAPTADRB2KDM4EADRB1 | |
| SCHEMBL8082807 | 0.80 | TSHR (0.77) | BLMCYP3A4TSHRPMP22NPSR1 | |
| SCHEMBL19236388 | 0.80 | ADRB2 (0.62) | TDP1ADRB2ADRB1CYP3A4TSHR | |
| SCHEMBL8847942 | 0.80 | MAPT (0.56) | TDP1MAPTADRB2KDM4EADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115120521-B | Polyphenol active composition and preparation method and application thereof | 广东省科学院化工研究所 | 2024-05-28 | — | — | CN | claimed |
| CN-115704004-A | Method for synthesizing phenylpropanol derivative by using immobilized enzyme | 杭州唯铂莱生物科技有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-115120521-B | Polyphenol active composition and preparation method and application thereof | 广东省科学院化工研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-115704004-A | Method for synthesizing phenylpropanol derivative by using immobilized enzyme | 杭州唯铂莱生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115120521-A | Polyphenol active composition and preparation method and application thereof | 广东省科学院化工研究所 | 2022-09-30 | — | — | CN | disclosed |