Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298914 | 0.92 | P2RX1 (0.41) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL14849968 | 0.89 | KMT2A (0.45) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL14850246 | 0.88 | ALDH1A1 (0.42) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL13968275 | 0.86 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL15073412 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL298242 | 0.84 | P2RX1 (0.44) | KMT2AMEN1L3MBTL1LMNACRHBP | |
| SCHEMBL13835559 | 0.84 | HTR1F (0.45) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL13968284 | 0.84 | SMN1; SMN2 (0.43) | KMT2AMEN1L3MBTL1MAPK1LMNA | |
| SCHEMBL13067830 | 0.83 | P2RX1 (0.42) | KMT2AMEN1L3MBTL1LMNACRHBP | |
| SCHEMBL19849002 | 0.83 | ALDH1A1 (0.42) | KMT2AMEN1L3MBTL1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339286-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | disclosed |
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2427426-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127928-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295907-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, BCHE | KMT2A 1857/4885MEN1 3134/4885L3MBTL1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.