Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991770 | 1.00 | LMNA (0.40) | LMNAMAPTHTR2BKMT2AMEN1 | |
| SCHEMBL2992766 | 1.00 | LMNA (0.40) | LMNAMAPTHTR2BKMT2AMEN1 | |
| SCHEMBL2994288 | 1.00 | LMNA (0.40) | LMNAMAPTHTR2BKMT2AMEN1 | |
| SCHEMBL2982818 | 1.00 | LMNA (0.40) | LMNAMAPTHTR2BKMT2AMEN1 | |
| SCHEMBL2987646 | 0.98 | CYP2C9 (0.38) | LMNAMAPTHTR2BKMT2AMEN1 | |
| SCHEMBL2990106 | 0.94 | CYP2C9 (0.40) | LMNAMAPTHTR2BKMT2ACYP3A4 | |
| SCHEMBL1733364 | 0.89 | LOX (0.41) | LMNAMAPTHTR2BKMT2APDE4D | |
| SCHEMBL1733377 | 0.89 | LOX (0.41) | LMNAMAPTHTR2BKMT2APDE4D | |
| SCHEMBL1735527 | 0.89 | LOX (0.41) | LMNAMAPTHTR2BKMT2APDE4D | |
| SCHEMBL1733376 | 0.89 | LOX (0.41) | LMNAMAPTHTR2BKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| CN-101553480-B | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC | 2013-06-05 | — | — | CN | disclosed |
| EP-2103608-B1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS INC (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| CN-101553480-A | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2103608-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | Arigen, Pharmaceuticals, Inc. (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | LMNA 4875/4885MAPT 4670/4885HTR2B 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.