Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21060104 | 1.00 | GPR119 (0.51) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29123341 | 0.95 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29897174 | 0.85 | ALOX5AP (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060372 | 0.85 | ALOX5AP (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060073 | 0.81 | HTR6 (0.36) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30675181 | 0.81 | HTR6 (0.36) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21062702 | 0.80 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30619899 | 0.80 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060267 | 0.79 | MAP4K4 (0.54) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30675155 | 0.79 | MAP4K4 (0.54) | GPR119NPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| US-11820768-B2 | 4-azaindole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
| US-20220340555-A1 | 4-AZAINDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820768-B2 | 4-azaindole compounds | TLR7, TLR9, TLR5 | GPR119 78/4885NPC1 3103/4885ALDH1A1 1039/4885 |
| US-20220340555-A1 | 4-AZAINDOLE COMPOUNDS | TLR7, TLR9, TLR5 | GPR119 78/4885NPC1 3103/4885ALDH1A1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.