Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29897166 | 0.95 | GPR119 (0.51) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060104 | 0.95 | GPR119 (0.51) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29897174 | 0.81 | ALOX5AP (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060372 | 0.81 | ALOX5AP (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL29123035 | 0.77 | TRPV3 (0.42) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060073 | 0.75 | HTR6 (0.36) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30675181 | 0.75 | HTR6 (0.36) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21062702 | 0.75 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL30619899 | 0.75 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21060414 | 0.74 | ALOX5AP (0.39) | GPR119NPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111819176-A | 4-azaindole compounds | 百时美施贵宝公司 | 2020-10-23 | — | — | CN | disclosed |