Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23301036 | 1.00 | PRKCZ (0.50) | PRKCZDYRK1ACCNA2CDK2BTK | |
| SCHEMBL25044342 | 0.92 | PRKCZ (0.49) | PRKCZDYRK1ABTKGPR119PIM1 | |
| SCHEMBL23328348 | 0.90 | DYRK1A (0.46) | PRKCZDYRK1ACCNA2CDK2BTK | |
| SCHEMBL23301073 | 0.88 | PRKCZ (0.54) | PRKCZROCK2CCR2ROCK1 | |
| SCHEMBL29897394 | 0.88 | BTK (0.44) | CCNA2CDK2BTKGPR119SYK | |
| SCHEMBL23301537 | 0.88 | BTK (0.44) | CCNA2CDK2BTKGPR119SYK | |
| SCHEMBL29897354 | 0.87 | ABL1 (0.46) | CCNA2CDK2BTKGPR119SYK | |
| SCHEMBL23301815 | 0.87 | ABL1 (0.46) | CCNA2CDK2BTKGPR119SYK | |
| SCHEMBL23301759 | 0.86 | GPR119 (0.49) | DYRK1ACCNA2CDK2BTKGPR119 | |
| SCHEMBL29897408 | 0.86 | GPR119 (0.49) | DYRK1ACCNA2CDK2BTKGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051664-A1 | ISOQUINOLINE DERIVATIVES AS SIK2 INHIBITORS | Cancer Research Technology Limited (GB) | 2022-09-07 | — | — | EP | disclosed |