Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F3 | P13726 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 2/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23301805 | 1.00 | F7 (0.38) | F7F3KDRPRKCZLMNA | |
| SCHEMBL23301507 | 0.81 | ALOX5AP (0.40) | — | |
| SCHEMBL29897405 | 0.81 | ALOX5AP (0.40) | — | |
| SCHEMBL29897440 | 0.79 | PRKCZ (0.43) | F7F3PRKCZLMNACYP1A2 | |
| SCHEMBL23301129 | 0.79 | PRKCZ (0.43) | F7F3PRKCZLMNACYP1A2 | |
| SCHEMBL23301031 | 0.75 | LMNA (0.46) | F7F3PRKCZLMNACYP1A2 | |
| SCHEMBL29897356 | 0.75 | LMNA (0.46) | F7F3PRKCZLMNACYP1A2 | |
| SCHEMBL29672398 | 0.73 | IMPDH2 (0.42) | PRKCZLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29930315 | 0.69 | MAP4K1 (0.49) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL23301086 | 0.68 | F7 (0.45) | F7F3LATS1LATS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051664-A1 | ISOQUINOLINE DERIVATIVES AS SIK2 INHIBITORS | Cancer Research Technology Limited (GB) | 2022-09-07 | — | — | EP | disclosed |