⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993732 | 0.74 | — | — | |
| SCHEMBL2996151 | 0.68 | CYP3A4 (0.37) | — | |
| SCHEMBL15021 | 0.68 | RAB9A (0.31) | — | |
| SCHEMBL9177820 | 0.64 | — | — | |
| SCHEMBL966903 | 0.64 | ACHE (0.41) | — | |
| SCHEMBL965199 | 0.64 | ACHE (0.37) | — | |
| SCHEMBL14615403 | 0.63 | ALDH1A1 (0.35) | — | |
| SCHEMBL968768 | 0.61 | ACHE (0.35) | — | |
| SCHEMBL7783627 | 0.61 | TYMS (0.31) | — | |
| SCHEMBL2458387 | 0.61 | ACHE (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786259-B2 | Attachment and elaboration strategies for inverse peptide synthesis | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080039612-A1 | ATTACHMENT AND ELABORATION STRATEGIES FOR INVERSE PEPTIDE SYNTHESIS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2008-02-14 | — | — | US | disclosed |
| US-7244815-B2 | Attachment and elaboration strategies for inverse peptide synthesis | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050027101-A1 | Attachment and elaboration strategies for inverse peptide synthesis | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2005-02-03 | — | — | US | disclosed |