Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631968 | 0.81 | POLB (0.42) | ALDH1A1MEN1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL1203340 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL3783930 | 0.76 | CA12 (0.42) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL8629611 | 0.76 | NPC1 (0.42) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL13242898 | 0.75 | SLC22A12 (0.32) | SLC22A12 | |
| SCHEMBL8633533 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP2C9SMN1; SMN2LMNANPC1 | |
| SCHEMBL10414873 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL3259116 | 0.73 | SMN1; SMN2 (0.35) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL8629590 | 0.72 | MAPT (0.41) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL28319827 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CYP2C9MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | claimed |
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100184973-A1 | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2167467-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-03-31 | — | — | EP | disclosed |
| CN-101687804-A | Method for producing dioxazine derivatives | BAYER CROPSCIENCE AG | 2010-03-31 | — | — | CN | disclosed |
| EP-2014658-A1 | Nicotinamide derivatives and method for their manufacture | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2009001-A1 | Method for manufacturing dioxazine derivatives | Bayer CropScience AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-2009001-A1 | Method for manufacturing dioxazine derivatives | Bayer CropScience AG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2008155004-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155004-A1 | METHOD FOR PRODUCING DIOXAZINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008155003-A1 | NICOTINAMIDE DERIVATIVES AS SYNTHESIS UNITS FOR PRODUCING AGROCHEMICAL SUBSTANCES, AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-12-24 | — | — | WO | disclosed |
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| CN-1108656-A | N-azinyl-N'-(HET)arylsulphonyl-ureas | BAYER AG (DE) | 1995-09-20 | — | — | CN | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190992-A1 | Nicotinamide derivatives as synthesis units for producing agrochemical substances, and method for the production thereof | NAMPT, NQO1, NNT | ALDH1A1 139/4885CYP2C9 262/4885MEN1 706/4885 |
| US-20100184973-A1 | Method for producing dioxazine derivatives | CYP4Z1, CYP1A1, CYP2F1 | ALDH1A1 127/4885CYP2C9 42/4885MEN1 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.