Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | BDKRB1 | P46663 | 16/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655848 | 0.73 | HSD17B10 (0.63) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 | |
| SCHEMBL27096399 | 0.73 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 | |
| SCHEMBL20870310 | 0.72 | HSD17B10 (0.52) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 | |
| SCHEMBL31488397 | 0.69 | HSD17B10 (1.00) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 | |
| SCHEMBL26656442 | 0.68 | BDKRB1 (0.36) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 | |
| SCHEMBL30101854 | 0.68 | BDKRB1 (0.49) | HSD17B10BDKRB1JAK1JAK3 | |
| SCHEMBL22225237 | 0.67 | HSD17B10 (0.51) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31469807 | 0.66 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28378376 | 0.65 | BDKRB1 (0.53) | HSD17B10BDKRB1 | |
| SCHEMBL22275075 | 0.65 | HSD17B10 (0.63) | KDM4EALDH1A1HSD17B10BDKRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111658653-B | Use of phosphodiesterase inhibitors | 药捷安康(南京)科技股份有限公司 | 2022-09-09 | — | — | CN | disclosed |