Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27096399 | 0.84 | ALDH1A1 (0.63) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL31488397 | 0.77 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL17824803 | 0.75 | KDM4E (0.53) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL28429236 | 0.74 | F2R (0.51) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL23885473 | 0.73 | PDK2 (0.44) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30254597 | 0.73 | PDK2 (0.44) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3457070 | 0.73 | ALDH1A1 (0.67) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL24578782 | 0.73 | ALDH1A1 (0.67) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL25383780 | 0.73 | KDM4E (0.49) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29901246 | 0.73 | KDM4E (0.52) | HSD17B10KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |